We know that X-Men Apocalypse isn't leading up to where we began our mutant journey with Patrick Stewart at the beginning of X-Men 1. When we watch the new Apocalypse trailer, the original trio of films shouldn't even be considered.
This film will re-write the X-Men history, or as Apocalypse producer Simon Kinberg explains it, "some things will be surprises; people could die that were alive in X-Men 1, 2 and 3,or people could survive that died during 1, 2 and 3.”
X-Men Apocalypse stars James McAvoy, Michael Fassbender, Oscar Isaac, Jennifer Lawrence, Olivia Munn, Tye Sheridan, Alexandra Shipp, Sophie Turner, Rose Byrne, and Nicholas Hoult. The film is set to premiere in theaters on May 27, 2016 and no, Deadpool won't be crossing over into the X-Men.