Boston and its surrounding area post-nuclear fallout can be a very dangerous place indeed. What with giant cockroaches and super mutants roaming around. Thankfully, the wasteland has some unique weapons of its own, you just have to know how to track them down.
Here is a list of most of the unique and rare weapons you can obtain in the game, with some helpful tips on how to acquire them.
Quick note: When I refer to a location on the map, I'm talking about the entirety of Commonwealth. When I say Boston, I'm only referring to the city itself in the middle and its northern outskirts.
Jamaica Plain, which is in the South East of the map. It's a reward under the Jamaica Plain City Hall.
A cave that's just East of Oberland Station on the West side of the map. Can be found once the nearby Crash Site has been investigated for Zetan activity.
The Castle, which is found in the South East part of Boston. Can be found during the Minutemen quest "Old Guns," inside the Castle's tunnels.
NH&M Freight Depot, which is in the South East part of the map. Reward for siding with or killing Farenheit at the of the side quest "The Big Dig."
The Castle, which is found in the South East part of Boston. Given to you by Sturges at the conclusion of the Minutement quest "The Nuclear Option."
Diamond City Market: Commonwealth Weaponry / Arturo's House, located in the South West part of Boston. Bought from vendor.
Walden Pond, located in the North West part of the map. Take a dive to find this weapon.
USS Constitution, found in the Northern part of Boston. You get this as a reward for completing the side quest "Last Voyage of the U.S.S. Constitution."
Vault 111. Can be obtained after you've gained the ability to unlock Master locks, or once you obtain Dogmeat. You can check out the guide here.
Prydwen, found in the North East part of the map. This weapon is sold by Proctor Teagan once you reach the rank of Paladin (Brotherhood of Steel)
Deathclaw Nest (Lynn Woods), found in the Northern part of the map. Reward for completing the side quest "The Devi's Due."
Old North Church, found in the North East part of Boston. A reward for completing the Railroad quest "Tradecraft."
Andrew Station, found in the South East part of Boston. A reward for removing Eddie during the side quest "Long Time Coming."
The Institute, found in the South East part of the map. Sold by the Institute Requisition vendor.
Prydwen, found in the North East part of the map. Carried by Elder Maxson. Remove it from him during the Institute quest "Airship Down" or the Railroad quest "Precipice of War."
Swan's Pond, found in the center of Boston. Remove the threat of Swan from Boston Common.
Parsons State Insane Asylum, found in the North part of the map. Reward for completing the side quest "The Secret of Cabot House."
Drumlin Diner, found in the North West part of the map. Settle the dispute with Trudy and you can purchase this serrated blade from her.
Quincy Ruins, found in the South East part of the map. Carried by the Gunner leader Clint on the elevated freeway camp.
Hubris Comics, found in Southern Boston. In the locked display case on the first floor. You'll need to be able to unlock Advanced locks.
HalluciGen, Inc. found in the North West part of Boston. You can craft these grenades at a Chemistry Workbench, but they require the HalluciGen Gas Canister obtained here.
Arcjet Systems, found in the West part of the map. Can be found in the utility room in the lower level of the Arcjet Engine Core. This is accessible during the Brotherhood of Steel quest "Call to Arms."
Fort Hagen, found in the West part of the map. Carried by Kellogg at this location. Kill him.
Dunwich Borers, found in the North West part of the map. Found in the darkest depths of this location.
Libertalia, found in the North East part of the map. Found in the Captain's cabin.
Parsons State Insane Asylum, found in the Northen section of the map. Reward for completing the side quest "The Secret of Cabot House."
Diamond City Market: Commonwealth Weaponry / Arturo's House, found in the West part of Boston. Sold by this vendor.
Goodneighbor, found just to the East of Central Boston. Sold by KL-E-0 at Kill or Be Killed.
Pickman Gallery, found in the North East part of Boston. Reward if you side with Pickman.
University Point, found in the South East part of Boston. It's inside a locked safe in the University Credit Union, requires Master unlock ability.
Old North Church, found in North East part of Boston. Reward for completing Railroad quest "Underground Undercover."
Rook Family House, found in the South East part of the map. Carried by Barney Rook.
Rook Family House, found in the South East part of the map. Reward for helping Barney during quest "Barney Rook."
Arcjet Systems, however the quest starts in the Police Station with the Brotherhood of Steel, found in the North West outskirts of Boston. You get this as a reward for completing the quest "Call to Arms."
Diamond City Market: Swatters, found in the Wester part of Boston. Sold by this vendor.
Prydwen, found in the North East part of the map. Sold by Proctor Teagan once you reach the rank of Sentinel (Brotherhood of Steel).
North End Graveyard, found in the North East part of Boston. Reward for completing the quest "The Gilded Grasshopper."
Saugus Ironworks, found in the North part of the map. Found in the Blast Furnace, carried by Slag.
Vault 81, found in the West part of the map. Complete the quest "Hole in the Wall."
Recon Bunker Theta, found in the North part of the map. You can obtain this by either killing Paladin Brandis, stealing it from him, or making him rejoin the Brotherhood of Steel in the quest "The Lost Patrol."
Quincy Poice Station, found in the South East part of the map. Carried by Tessa, so you know what to do.
Vitale Pumphouse, found in the North East part of the map. Solve the number puzzle and this weapon can be found in the room with the steamer trunk.
Prydwen, found in the North East part of the map. Reward for completing the Brotherhood of Steel quest "Show no Mercy." Can also be obtained by siding with the Railroad or Minutemen in the removal of Prydwen.
Rocky Cave, found in Virgil's Laboratory in the South West part of the map. Kill Virgil or steal it from him.
Bunker Hill, found in the Northern part of Boston. Sold by Deb.
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